Hakai overexpression effectively induces tumour progression and metastasis in vivo
Abstract At early stages of carcinoma progression, epithelial cells undergo a program named epithelial-to-mesenchymal transition characterized by the loss of the major component of the adherens junctions, E-cadherin, which in consequence causes the disruption of cell-cell contacts. Hakai is an E3 ub...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/2673c8d402fa48a18d278383f492cfe5 |
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