Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites.

Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity of natural products (NPs) and medicinal plants used in traditional medicine f...

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Autores principales: María Lorena Cordero-Maldonado, Dany Siverio-Mota, Liliana Vicet-Muro, Isabel María Wilches-Arizábala, Camila V Esguerra, Peter A M de Witte, Alexander D Crawford
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/26aee21c95e4484e8ab1dc7f4c6a5ba5
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