Histone deacetylase 6 (HDAC6) is an essential factor for oocyte maturation and asymmetric division in mice

Abstract Tubastatin A (Tub-A), a highly selective histone deacetylase 6 (HDAC6) inhibitor, has been widely used as a cytotoxic anticancer agent, or for the treatment of patients with asthma. However, the potential toxicity of Tub-A on oocyte maturation and asymmetric division is still unclear. There...

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Autores principales: Dongjie Zhou, Yun-Jung Choi, Jin-Hoi Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/26af42e37017422b90f02f3e7c81edb5
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