The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells.

The LIM-only protein FHL2, also known as DRAL or SLIM3, has a function in fine-tuning multiple physiological processes. FHL2 is expressed in the vessel wall in smooth muscle cells (SMCs) and endothelial cells and conflicting data have been reported on the regulatory function of FHL2 in SMC phenotype...

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Auteurs principaux: Kondababu Kurakula, Mariska Vos, Iker Otermin Rubio, Goran Marinković, Reinhard Buettner, Lukas C Heukamp, Jan Stap, Vivian de Waard, Claudia M van Tiel, Carlie J M de Vries
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/26b213cef63945599aa7e3cec543a1a3
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