The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins Mrc1/Tof1/Csm3.

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Autores principales: Anjana Srivatsan, Bin-Zhong Li, Barnabas Szakal, Dana Branzei, Christopher D. Putnam, Richard D. Kolodner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/26b3c91b973843c4a9d010d3be601fc1
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