The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins Mrc1/Tof1/Csm3.

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Autores principales:	Anjana Srivatsan, Bin-Zhong Li, Barnabas Szakal, Dana Branzei, Christopher D. Putnam, Richard D. Kolodner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/26b3c91b973843c4a9d010d3be601fc1
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spelling	oai:doaj.org-article:26b3c91b973843c4a9d010d3be601fc12021-12-02T16:49:32ZThe Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects10.1038/s41467-018-06131-22041-1723https://doaj.org/article/26b3c91b973843c4a9d010d3be601fc12018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06131-2https://doaj.org/toc/2041-1723SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins Mrc1/Tof1/Csm3.Anjana SrivatsanBin-Zhong LiBarnabas SzakalDana BranzeiChristopher D. PutnamRichard D. KolodnerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anjana Srivatsan Bin-Zhong Li Barnabas Szakal Dana Branzei Christopher D. Putnam Richard D. Kolodner The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
description	SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins Mrc1/Tof1/Csm3.
format	article
author	Anjana Srivatsan Bin-Zhong Li Barnabas Szakal Dana Branzei Christopher D. Putnam Richard D. Kolodner
author_facet	Anjana Srivatsan Bin-Zhong Li Barnabas Szakal Dana Branzei Christopher D. Putnam Richard D. Kolodner
author_sort	Anjana Srivatsan
title	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
title_short	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
title_full	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
title_fullStr	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
title_full_unstemmed	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
title_sort	swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/26b3c91b973843c4a9d010d3be601fc1
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The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

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