Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils.

Increasing evidence indicates that oligomeric protein assemblies may represent the molecular species responsible for cytotoxicity in a range of neurological disorders including Alzheimer and Parkinson diseases. We use all-atom computer simulations to reveal that the process of oligomerization can be...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mookyung Cheon, Iksoo Chang, Sandipan Mohanty, Leila M Luheshi, Christopher M Dobson, Michele Vendruscolo, Giorgio Favrin
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
Materias:
Acceso en línea:https://doaj.org/article/26e62cab93244385a7f6815d4adeb4f9
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!