Strategic cell-cycle regulatory features that provide mammalian cells with tunable G1 length and reversible G1 arrest.

Transitions between consecutive phases of the eukaryotic cell cycle are driven by the catalytic activity of selected sets of cyclin-dependent kinases (Cdks). Yet, their occurrence and precise timing is tightly scheduled by a variety of means including Cdk association with inhibitory/adaptor proteins...

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Autor principal: Benjamin Pfeuty
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/26ec3abe1fed48fcbc996d3cd5077712
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