CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution

Our structural understanding of class A penicillin binding proteins is incomplete due to the difficulty in their crystallization and the complexity of their substrates. Here, authors determine the structure of the 83 kDa class A PBP from Escherichia coli, PBP1b, using cryogenic electron microscopy a...

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Autores principales: Nathanael A. Caveney, Sean D. Workman, Rui Yan, Claire E. Atkinson, Zhiheng Yu, Natalie C. J. Strynadka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/26f4e40c535f443f997600b2ad246b01
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