Hydroxynonenal causes Langerhans cell degeneration in the pancreas of Japanese macaque monkeys

<h4>Background</h4> For their functions of insulin biosynthesis and glucose- and fatty acid- mediated insulin secretion, Langerhans β-cells require an intracellular milieu rich in oxygen. This requirement makes β-cells, with their constitutively low antioxidative defense, susceptible to...

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Auteurs principaux: Piyakarn Boontem, Tetsumori Yamashima
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/272822dbc3e949289d27afb930befbf1
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