Hydroxynonenal causes Langerhans cell degeneration in the pancreas of Japanese macaque monkeys
<h4>Background</h4> For their functions of insulin biosynthesis and glucose- and fatty acid- mediated insulin secretion, Langerhans β-cells require an intracellular milieu rich in oxygen. This requirement makes β-cells, with their constitutively low antioxidative defense, susceptible to...
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Autores principales: | Piyakarn Boontem, Tetsumori Yamashima |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/272822dbc3e949289d27afb930befbf1 |
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