Fates of retroviral core components during unrestricted and TRIM5-restricted infection.

TRIM5 proteins can restrict retroviral infection soon after delivery of the viral core into the cytoplasm. However, the molecular mechanisms by which TRIM5α inhibits infection have been elusive, in part due to the difficulty of developing and executing biochemical assays that examine this stage of t...

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Auteurs principaux: Sebla B Kutluay, David Perez-Caballero, Paul D Bieniasz
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/273780abbffe4f918789c7230f890c8b
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