Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations

Abstract The effect of scheduling of targeted therapy combinations on drug resistance is underexplored in triple-negative breast cancer (TNBC). TNBC constitutes heterogeneous cancer cell populations the composition of which can change dynamically during treatment resulting in the selection of resist...

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Bibliographic Details
Main Authors: Gauri A. Patwardhan, Michal Marczyk, Vikram B. Wali, David F. Stern, Lajos Pusztai, Christos Hatzis
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/2761058a831d4c5bb0c7d0fdb6e51e5e
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