Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder.

Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder.

<h4>Background</h4>Panic disorder is common (5% prevalence) and females are twice as likely to be affected as males. The heritable component of panic disorder is estimated at 48%. Glutamic acid dehydrogenase GAD1, the key enzyme for the synthesis of the inhibitory and anxiolytic neurotra...

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Main Authors: Heike Weber, Claus Jürgen Scholz, Katharina Domschke, Christian Baumann, Benedikt Klauke, Christian P Jacob, Wolfgang Maier, Jürgen Fritze, Borwin Bandelow, Peter Michael Zwanzger, Thomas Lang, Lydia Fehm, Andreas Ströhle, Alfons Hamm, Alexander L Gerlach, Georg W Alpers, Tilo Kircher, Hans-Ulrich Wittchen, Volker Arolt, Paul Pauli, Jürgen Deckert, Andreas Reif
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/276ac9b10ca449b19630d103d87b9fa9
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