NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies

ABSTRACT Neisseria meningitidis serogroup B (MenB) is a major cause of sepsis and invasive meningococcal disease. A multicomponent vaccine, 4CMenB, is approved for protection against MenB. Neisserial adhesin A (NadA) is one of the main vaccine antigens, acts in host cell adhesion, and may influence...

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Autores principales: Alessia Liguori, Lucia Dello Iacono, Giulietta Maruggi, Barbara Benucci, Marcello Merola, Paola Lo Surdo, Jacinto López-Sagaseta, Mariagrazia Pizza, Enrico Malito, Matthew J. Bottomley
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://doaj.org/article/27786e9b8cd34730b7b46d70ceb020ba
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