Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay.

<h4>Background</h4>Phosphatidic acid (PA) is a key regulated intermediate and precursor for de novo biosynthesis of all glycerophospholipids. PA can be synthesized through the acylation of lysophosphatidic acid (LPA) by 1-acyl-3-phosphate acyltransferase (also called lysophosphatidic aci...

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Main Authors: Guanghou Shui, Xue Li Guan, Pradeep Gopalakrishnan, Yangkui Xue, Joyce Sze Yuin Goh, Hongyuan Yang, Markus R Wenk
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
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Online Access:https://doaj.org/article/2786d2948ab445de925fdc46def295f5
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