Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin

ABSTRACT Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway. Prior studies showed that MBL-dependent activ...

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Autores principales: Panisadee Avirutnan, Richard E. Hauhart, Mary A. Marovich, Peter Garred, John P. Atkinson, Michael S. Diamond
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/279688e46b7245ec86fc1f48e0260ec0
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