Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes

Abstract PTEN has a strong Mendelian association with autism spectrum disorder (ASD), representing a special case in autism’s complex genetic architecture. Animal modeling for constitutional Pten mutation creates an opportunity to study how disruption of Pten affects neurobiology and glean potential...

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Auteurs principaux: Stetson Thacker, Charis Eng
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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R
Accès en ligne:https://doaj.org/article/27a1671a0c874649a0fa9e2d133d2d64
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