EGFR soluble isoforms and their transcripts are expressed in meningiomas.

The EGFR (epidermal growth factor receptor) is involved in the oncogenesis of many tumors. In addition to the full-length EGFR (isoform a), normal and tumor cells produce soluble EGFR isoforms (sEGFR) that lack the intracellular domain. sEGFR isoforms b, c and d are encoded by EGFR variants 2 (v2),...

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Autores principales: Angélique Guillaudeau, Karine Durand, Barbara Bessette, Alain Chaunavel, Isabelle Pommepuy, Fabrice Projetti, Sandrine Robert, François Caire, Hélène Rabinovitch-Chable, François Labrousse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/27b31970fd2649008dc0c26cd0566914
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