EGFR soluble isoforms and their transcripts are expressed in meningiomas.
The EGFR (epidermal growth factor receptor) is involved in the oncogenesis of many tumors. In addition to the full-length EGFR (isoform a), normal and tumor cells produce soluble EGFR isoforms (sEGFR) that lack the intracellular domain. sEGFR isoforms b, c and d are encoded by EGFR variants 2 (v2),...
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Autores principales: | Angélique Guillaudeau, Karine Durand, Barbara Bessette, Alain Chaunavel, Isabelle Pommepuy, Fabrice Projetti, Sandrine Robert, François Caire, Hélène Rabinovitch-Chable, François Labrousse |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/27b31970fd2649008dc0c26cd0566914 |
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