Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans

Cross-Reactive Antibodies to SARS-CoV-2 and MERS-CoV in Pre-COVID-19 Blood Samples from Sierra Leoneans

Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger population could partly account for these differences, but pre-existing immunity to coronaviruses is another potential fac...

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Main Authors: Rodrigo Borrega, Diana K. S. Nelson, Anatoliy P. Koval, Nell G. Bond, Megan L. Heinrich, Megan M. Rowland, Raju Lathigra, Duane J. Bush, Irina Aimukanova, Whitney N. Phinney, Sophia A. Koval, Andrew R. Hoffmann, Allison R. Smither, Antoinette R. Bell-Kareem, Lilia I. Melnik, Kaylynn J. Genemaras, Karissa Chao, Patricia Snarski, Alexandra B. Melton, Jaikin E. Harrell, Ashley A. Smira, Debra H. Elliott, Julie A. Rouelle, Gilberto Sabino-Santos, Arnaud C. Drouin, Mambu Momoh, John Demby Sandi, Augustine Goba, Robert J. Samuels, Lansana Kanneh, Michael Gbakie, Zoe L. Branco, Jeffrey G. Shaffer, John S. Schieffelin, James E. Robinson, Dahlene N. Fusco, Pardis C. Sabeti, Kristian G. Andersen, Donald S. Grant, Matthew L. Boisen, Luis M. Branco, Robert F. Garry
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
COVID-19 caseloads and deaths
sub-Saharan Africa
pre-existing immunity to coronaviruses
recombinant antigens
enzyme-linked immunosorbent assays
pseudovirus neutralizing antibodies
Microbiology
QR1-502
Online Access:https://doaj.org/article/27d9109965114b0bbc7de5dfd8613f6a
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https://doaj.org/article/27d9109965114b0bbc7de5dfd8613f6a

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