Enhancement of asynchronous release from fast-spiking interneuron in human and rat epileptic neocortex.

Down-regulation of GABAergic inhibition may result in the generation of epileptiform activities. Besides spike-triggered synchronous GABA release, changes in asynchronous release (AR) following high-frequency discharges may further regulate epileptiform activities. In brain slices obtained from surg...

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Autores principales: Man Jiang, Jie Zhu, Yaping Liu, Mingpo Yang, Cuiping Tian, Shan Jiang, Yonghong Wang, Hui Guo, Kaiyan Wang, Yousheng Shu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/27e43aacf71547879dfee2470702ea06
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