A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds

A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds

The development of an in vitro system for the study of lung vascular disease is critical to understanding human pathologies. Conventional culture systems fail to fully recapitulate native microenvironmental conditions and are typically limited in their ability to represent human pathophysiology for...

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Bibliographic Details
Main Authors: Yifan Yuan, Katherine L. Leiby, Allison M. Greaney, Micha Sam Brickman Raredon, Hong Qian, Jonas C. Schupp, Alexander J. Engler, Pavlina Baevova, Taylor S. Adams, Mehmet H. Kural, Juan Wang, Tomohiro Obata, Mervin C. Yoder, Naftali Kaminski, Laura E. Niklason
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
whole lung tissue engineering
endothelium
pulmonary vasculature
in vitro disease modeling
single-cell RNA-sequencing
Biotechnology
TP248.13-248.65
Online Access:https://doaj.org/article/27fd7b2723344f87ac6ed4658c43120a
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https://doaj.org/article/27fd7b2723344f87ac6ed4658c43120a

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