MMP9 Differentially Regulates Proteins Involved in Actin Polymerization and Cell Migration during TGF-β-Induced EMT in the Lens

Fibrotic cataracts have been attributed to transforming growth factor-beta (TGF-β)-induced epithelial-to-mesenchymal transition (EMT). Using mouse knockout (KO) models, our laboratory has identified MMP9 as a crucial protein in the TGF-β-induced EMT process. In this study, we further revealed an abs...

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Autores principales: Zi Zhen (Ginny) Liu, Aftab Taiyab, Judith A. West-Mays
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
EMT
PCO
Acceso en línea:https://doaj.org/article/280609783340456ba2978db6d68b59bb
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