Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers

Although detection of pathogens by pattern recognition receptors is increasingly well defined, recognition of endogenous triggers remains poorly understood. By examining the interface between tenascin-C and TLR4, the authors identify a molecular code that identifies endogenous proteins as inflammato...

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Bibliographic Details
Main Authors: Lorena Zuliani-Alvarez, Anna M. Marzeda, Claire Deligne, Anja Schwenzer, Fiona E. McCann, Brian D. Marsden, Anna M. Piccinini, Kim S. Midwood
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/280b5571ad664b09ab67b12a008edf59
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