Pan-cancer analysis of genomic properties and clinical outcome associated with tumor tertiary lymphoid structure

Abstract How the genomic landscape of a tumor shapes the formation of tertiary lymphoid structure (TLS) and how might TLS alter the clinical outcome or response to immunotherapy had not been systematically explored. Utilizing the genomic and transcriptome data of solid tumors on TCGA, we quantified...

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Autores principales: Ziying Lin, Lixia Huang, ShaoLi Li, Jincui Gu, Xiaoxian Cui, Yanbin Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/28125f730e6c4ecfa912e3a8af52d5a8
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