E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

The arrival of migratory cells at their targets relies on following precise routes within tissues. Here the authors demonstrate that the cell adhesion molecule E-cadherin can control the path of cell migration by confining the site where bleb-type protrusions form within the cell front.

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Bibliographic Details
Main Authors: Cecilia Grimaldi, Isabel Schumacher, Aleix Boquet-Pujadas, Katsiaryna Tarbashevich, Bart Eduard Vos, Jan Bandemer, Jan Schick, Anne Aalto, Jean-Christophe Olivo-Marin, Timo Betz, Erez Raz
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/28360082faba432bb37092c10016f635
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