Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Promoted Osteogenesis by Increasing Vesicle Trafficking, Wnt/Ca<sup>2+</sup>, and BMP/Smad Signaling

Sphingosine-1-phosphate receptor 2 (S1PR2) is a G protein-coupled receptor that regulates various immune responses. Herein, we determine the effects of a S1PR2 antagonist (JTE013) or a S1PR2 shRNA on osteogenesis by culturing murine bone marrow stromal cells (BMSCs) in osteogenic media with JTE013,...

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Autores principales: Simon Lin, Subramanya Pandruvada, Hong Yu
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Wnt
Acceso en línea:https://doaj.org/article/28f43dc6f0ea46f0a3b480db16276085
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