Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Promoted Osteogenesis by Increasing Vesicle Trafficking, Wnt/Ca<sup>2+</sup>, and BMP/Smad Signaling
Sphingosine-1-phosphate receptor 2 (S1PR2) is a G protein-coupled receptor that regulates various immune responses. Herein, we determine the effects of a S1PR2 antagonist (JTE013) or a S1PR2 shRNA on osteogenesis by culturing murine bone marrow stromal cells (BMSCs) in osteogenic media with JTE013,...
Guardado en:
Autores principales: | Simon Lin, Subramanya Pandruvada, Hong Yu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/28f43dc6f0ea46f0a3b480db16276085 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Biogenesis, Membrane Trafficking, Functions, and Next Generation Nanotherapeutics Medicine of Extracellular Vesicles
por: Gurunathan S, et al.
Publicado: (2021) -
CD63<sup>+</sup> and MHC Class I<sup>+</sup> Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression
por: Sukhbir Kaur, et al.
Publicado: (2021) -
INCRIMINACIÓN DEL MALTRATO CORPORAL RELEVANTE Y DE LA SUMISIÓN A TRATO DEGRADANTE DE PERSONAS CON DÉFICIT CORPORAL O FÍSICO EN LA LEGISLACIÓN PENAL CHILENA. LEY N°21.013 DE 2017
por: CARRASCO-JIMÉNEZ,EDISON
Publicado: (2018) -
System-Wide Characterization of MoArf GTPase Family Proteins and Adaptor Protein MoGga1 Involved in the Development and Pathogenicity of <named-content content-type="genus-species">Magnaporthe oryzae</named-content>
por: Shengpei Zhang, et al.
Publicado: (2019) -
Forced association of SARS-CoV-2 proteins with the yeast proteome perturb vesicle trafficking
por: Cinzia Klemm, et al.
Publicado: (2021)