Differential metabolic responses in breast cancer cell lines to acidosis and lactic acidosis revealed by stable isotope assisted metabolomics

Abstract Extracellular acidosis is considered as a hallmark of most human tumors, which plays an important role in promoting tumor malignant and aggressive phenotype in tumorigenesis. Acidosis and lactic acidosis can induce different responses in tumors. Previous studies have associated the response...

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Bibliographic Details
Main Authors: Jiayue Gao, Zhiying Guo, Jianhua Cheng, Bo Sun, Jie Yang, Haijing Li, Shengming Wu, Fangting Dong, Xianzhong Yan
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/28fe4e63b1e9451797c86c56443a17e8
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