Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide

Abstract Nimesulide is an inhibitor of COX-2 with antioxidant and anti-inflammatory effects. However, few studies have explored the antidepressant mechanism of nimesulide. Here, we evaluated the therapeutic effects of nimesulide on CUMS rats. iTRAQ technology was used to identify the differentially...

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Détails bibliographiques
Auteurs principaux: Wen Luo, Ying Luo, Junqing Yang
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/2904b7fe732740e892b41441350fcaaf
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