Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide

Abstract Nimesulide is an inhibitor of COX-2 with antioxidant and anti-inflammatory effects. However, few studies have explored the antidepressant mechanism of nimesulide. Here, we evaluated the therapeutic effects of nimesulide on CUMS rats. iTRAQ technology was used to identify the differentially...

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Autores principales: Wen Luo, Ying Luo, Junqing Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2904b7fe732740e892b41441350fcaaf
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