Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide

Abstract Nimesulide is an inhibitor of COX-2 with antioxidant and anti-inflammatory effects. However, few studies have explored the antidepressant mechanism of nimesulide. Here, we evaluated the therapeutic effects of nimesulide on CUMS rats. iTRAQ technology was used to identify the differentially...

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Bibliographic Details
Main Authors: Wen Luo, Ying Luo, Junqing Yang
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/2904b7fe732740e892b41441350fcaaf
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