The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

<h4>Background</h4>Methotrexate is a chemotherapeutic agent used to treat a variety of cancers. However, the occurrence of resistance limits its effectiveness. Cytochrome c in its reduced state is less capable of triggering the apoptotic cascade. Thus, we set up to study the relationship...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Susana Barros, Núria Mencia, Laura Rodríguez, Carlota Oleaga, Conceição Santos, Verónique Noé, Carlos J Ciudad
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
R
Q
Acceso en línea:https://doaj.org/article/290a7a44e3a7489390dae166c1043b02
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!