Combinatorial Approaches to Viral Attenuation

ABSTRACT Attenuated viruses have numerous applications, in particular in the context of live viral vaccines. However, purposefully designing attenuated viruses remains challenging, in particular if the attenuation is meant to be resistant to rapid evolutionary recovery. Here we develop and analyze a...

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Autores principales: Matthew L. Paff, Benjamin R. Jack, Bartram L. Smith, James J. Bull, Claus O. Wilke
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://doaj.org/article/291200245dde4ac385767d4c89da75c5
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