Bi-directional ribosome scanning controls the stringency of start codon selection
Start codon selection is commonly thought to occur through the unidirectional scanning of the mRNA by the 40 S ribosome. Here the authors provide evidence that the pre-initiation complex can backslide on the mRNA to initiate translation at upstream AUG codons.
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Autores principales: | Yifei Gu, Yuanhui Mao, Longfei Jia, Leiming Dong, Shu-Bing Qian |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/291d39793d7a4dbc85968755a40300d0 |
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