Robust and sensitive analysis of mouse knockout phenotypes.

A significant challenge of in-vivo studies is the identification of phenotypes with a method that is robust and reliable. The challenge arises from practical issues that lead to experimental designs which are not ideal. Breeding issues, particularly in the presence of fertility or fecundity problems...

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Bibliographic Details
Main Authors: Natasha A Karp, David Melvin, Sanger Mouse Genetics Project, Richard F Mott
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/2932fb5980634f9490cd10fcf47d8740
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