Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells
T follicular regulatory cells control the magnitude of the germinal centre response. Here the authors show that these cells display specificity to self as well as foreign antigens, and can arise from Foxp3-negative precursors at early stages of immunization in a PD-L1 dependent manner.
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/295284e73c8a4c66a06393b19e2b2e67 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|