Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1.
High mobility group box-1 (HMGB1) is associated with the pathogenesis of inflammatory diseases. A previous study reported that intravenous injection of anti-HMGB1 monoclonal antibody significantly attenuated brain edema in a rat model of stroke, possibly by attenuating glial activation. Peripheral n...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/2965180cbf494cef9964274dbf958284 |
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