CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites

ABSTRACT Toxoplasma gondii and members of the genus Plasmodium are obligate intracellular parasites that leave their infected host cell upon a tightly controlled process of egress. Intracellular replication of the parasites occurs within a parasitophorous vacuole, and its membrane as well as the hos...

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Autores principales: Paul-Christian Burda, Hugo Bisio, Jean-Baptiste Marq, Dominique Soldati-Favre, Volker T. Heussler
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/2982922e725b40bf8593d040936cc872
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