Cholesterol-dependent plasma membrane order (Lo) is critical for antigen-specific clonal expansion of CD4+ T cells

Abstract Early “T cell activation” events are initiated within the lipid microenvironment of the plasma membrane. Role of lipid membrane order (Lo) in spatiotemporal signaling through the antigen receptor in T cells is posited but remains unclear. We have examined the role of membrane order (Lo)/dis...

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Auteurs principaux: Soumini Sengupta, Ritesh Karsalia, Amanda Morrissey, Anil K. Bamezai
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/29be056c74c94ae0b4f0c8490a3f5777
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