Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein
Tardigrades are resistant to extreme environmental conditions including dehydration, radiation and the vacuum of space. Here the authors present a high-quality genome which displays minimal horizontal gene transfer, and identify the unique tardigrade protein Dsup which suppresses DNA damage.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/29c031cfa4904104a798649f99ba60cf |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:29c031cfa4904104a798649f99ba60cf |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:29c031cfa4904104a798649f99ba60cf2021-12-02T17:32:38ZExtremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein10.1038/ncomms128082041-1723https://doaj.org/article/29c031cfa4904104a798649f99ba60cf2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12808https://doaj.org/toc/2041-1723Tardigrades are resistant to extreme environmental conditions including dehydration, radiation and the vacuum of space. Here the authors present a high-quality genome which displays minimal horizontal gene transfer, and identify the unique tardigrade protein Dsup which suppresses DNA damage.Takuma HashimotoDaiki D. HorikawaYuki SaitoHirokazu KuwaharaHiroko Kozuka-HataTadasu Shin-IYohei MinakuchiKazuko OhishiAyuko MotoyamaTomoyuki AizuAtsushi EnomotoKoyuki KondoSae TanakaYuichiro HaraShigeyuki KoshikawaHiroshi SagaraToru MiuraShin-ichi YokoboriKiyoshi MiyagawaYutaka SuzukiTakeo KuboMasaaki OyamaYuji KoharaAsao FujiyamaKazuharu ArakawaToshiaki KatayamaAtsushi ToyodaTakekazu KuniedaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Takuma Hashimoto Daiki D. Horikawa Yuki Saito Hirokazu Kuwahara Hiroko Kozuka-Hata Tadasu Shin-I Yohei Minakuchi Kazuko Ohishi Ayuko Motoyama Tomoyuki Aizu Atsushi Enomoto Koyuki Kondo Sae Tanaka Yuichiro Hara Shigeyuki Koshikawa Hiroshi Sagara Toru Miura Shin-ichi Yokobori Kiyoshi Miyagawa Yutaka Suzuki Takeo Kubo Masaaki Oyama Yuji Kohara Asao Fujiyama Kazuharu Arakawa Toshiaki Katayama Atsushi Toyoda Takekazu Kunieda Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| description |
Tardigrades are resistant to extreme environmental conditions including dehydration, radiation and the vacuum of space. Here the authors present a high-quality genome which displays minimal horizontal gene transfer, and identify the unique tardigrade protein Dsup which suppresses DNA damage. |
| format |
article |
| author |
Takuma Hashimoto Daiki D. Horikawa Yuki Saito Hirokazu Kuwahara Hiroko Kozuka-Hata Tadasu Shin-I Yohei Minakuchi Kazuko Ohishi Ayuko Motoyama Tomoyuki Aizu Atsushi Enomoto Koyuki Kondo Sae Tanaka Yuichiro Hara Shigeyuki Koshikawa Hiroshi Sagara Toru Miura Shin-ichi Yokobori Kiyoshi Miyagawa Yutaka Suzuki Takeo Kubo Masaaki Oyama Yuji Kohara Asao Fujiyama Kazuharu Arakawa Toshiaki Katayama Atsushi Toyoda Takekazu Kunieda |
| author_facet |
Takuma Hashimoto Daiki D. Horikawa Yuki Saito Hirokazu Kuwahara Hiroko Kozuka-Hata Tadasu Shin-I Yohei Minakuchi Kazuko Ohishi Ayuko Motoyama Tomoyuki Aizu Atsushi Enomoto Koyuki Kondo Sae Tanaka Yuichiro Hara Shigeyuki Koshikawa Hiroshi Sagara Toru Miura Shin-ichi Yokobori Kiyoshi Miyagawa Yutaka Suzuki Takeo Kubo Masaaki Oyama Yuji Kohara Asao Fujiyama Kazuharu Arakawa Toshiaki Katayama Atsushi Toyoda Takekazu Kunieda |
| author_sort |
Takuma Hashimoto |
| title |
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| title_short |
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| title_full |
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| title_fullStr |
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| title_full_unstemmed |
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| title_sort |
extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/29c031cfa4904104a798649f99ba60cf |
| work_keys_str_mv |
AT takumahashimoto extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT daikidhorikawa extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT yukisaito extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT hirokazukuwahara extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT hirokokozukahata extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT tadasushini extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT yoheiminakuchi extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT kazukoohishi extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT ayukomotoyama extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT tomoyukiaizu extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT atsushienomoto extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT koyukikondo extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT saetanaka extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT yuichirohara extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT shigeyukikoshikawa extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT hiroshisagara extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT torumiura extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT shinichiyokobori extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT kiyoshimiyagawa extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT yutakasuzuki extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT takeokubo extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT masaakioyama extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT yujikohara extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT asaofujiyama extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT kazuharuarakawa extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT toshiakikatayama extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT atsushitoyoda extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein AT takekazukunieda extremotoleranttardigradegenomeandimprovedradiotoleranceofhumanculturedcellsbytardigradeuniqueprotein |
| _version_ |
1718380236410716160 |