Humanising the mouse genome piece by piece

Generation of transgenic mice has become routine in studying gene function and disease mechanisms, but often this is not enough to fully understand human biology. Here, the authors review the current state of the art of targeted genomic humanisation strategies and their advantages over classic appro...

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Auteurs principaux: Fei Zhu, Remya R. Nair, Elizabeth M. C. Fisher, Thomas J. Cunningham
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
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Accès en ligne:https://doaj.org/article/29c79726f62740aba33706a6284e124b
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