Humanising the mouse genome piece by piece
Generation of transgenic mice has become routine in studying gene function and disease mechanisms, but often this is not enough to fully understand human biology. Here, the authors review the current state of the art of targeted genomic humanisation strategies and their advantages over classic appro...
Guardado en:
Autores principales: | Fei Zhu, Remya R. Nair, Elizabeth M. C. Fisher, Thomas J. Cunningham |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/29c79726f62740aba33706a6284e124b |
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