M Protein and Hyaluronic Acid Capsule Are Essential for <italic toggle="yes">In Vivo</italic> Selection of <italic toggle="yes">covRS</italic> Mutations Characteristic of Invasive Serotype M1T1 Group A <italic toggle="yes">Streptococcus</italic>
ABSTRACT The initiation of hyperinvasive disease in group A Streptococcus (GAS) serotype M1T1 occurs by mutation within the covRS two-component regulon (named covRS for control of virulence regulatory sensor kinase), which promotes resistance to neutrophil-mediated killing through the upregulation o...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2010
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| Accès en ligne: | https://doaj.org/article/29d2718b948441769760790a55214328 |
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