Ciliary genes are down-regulated in bronchial tissue of primary ciliary dyskinesia patients.

Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous disease characterized by recurrent respiratory tract infections, sinusitis, bronchiectasis and male infertility. The pulmonary phenotype in PCD is caused by the impaired motility of cilia in the respiratory epithelium, due to ultr...

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Autores principales: Maciej Geremek, Ewa Ziętkiewicz, Marcel Bruinenberg, Lude Franke, Andrzej Pogorzelski, Cisca Wijmenga, Michał Witt
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/2a06e777525841138ad257adcf4b7d9d
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