Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging

Influenza A virus (IAV) packages its eight genomic RNA segments in a specific “1+7” pattern. Here, the authors generate IAV that lack one RNA segment and show that ribosomal RNA is packaged in place of the eighth segment, suggesting that the 1+7 pattern is important for particle production.

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Autores principales:	Takeshi Noda, Shin Murakami, Sumiho Nakatsu, Hirotaka Imai, Yukiko Muramoto, Keiko Shindo, Hiroshi Sagara, Yoshihiro Kawaoka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2a145101eed44b61997b802d91bc2974
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spelling	oai:doaj.org-article:2a145101eed44b61997b802d91bc29742021-12-02T17:31:26ZImportance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging10.1038/s41467-017-02517-w2041-1723https://doaj.org/article/2a145101eed44b61997b802d91bc29742018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02517-whttps://doaj.org/toc/2041-1723Influenza A virus (IAV) packages its eight genomic RNA segments in a specific “1+7” pattern. Here, the authors generate IAV that lack one RNA segment and show that ribosomal RNA is packaged in place of the eighth segment, suggesting that the 1+7 pattern is important for particle production.Takeshi NodaShin MurakamiSumiho NakatsuHirotaka ImaiYukiko MuramotoKeiko ShindoHiroshi SagaraYoshihiro KawaokaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Takeshi Noda Shin Murakami Sumiho Nakatsu Hirotaka Imai Yukiko Muramoto Keiko Shindo Hiroshi Sagara Yoshihiro Kawaoka Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
description	Influenza A virus (IAV) packages its eight genomic RNA segments in a specific “1+7” pattern. Here, the authors generate IAV that lack one RNA segment and show that ribosomal RNA is packaged in place of the eighth segment, suggesting that the 1+7 pattern is important for particle production.
format	article
author	Takeshi Noda Shin Murakami Sumiho Nakatsu Hirotaka Imai Yukiko Muramoto Keiko Shindo Hiroshi Sagara Yoshihiro Kawaoka
author_facet	Takeshi Noda Shin Murakami Sumiho Nakatsu Hirotaka Imai Yukiko Muramoto Keiko Shindo Hiroshi Sagara Yoshihiro Kawaoka
author_sort	Takeshi Noda
title	Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
title_short	Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
title_full	Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
title_fullStr	Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
title_full_unstemmed	Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging
title_sort	importance of the 1+7 configuration of ribonucleoprotein complexes for influenza a virus genome packaging
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2a145101eed44b61997b802d91bc2974
work_keys_str_mv	AT takeshinoda importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT shinmurakami importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT sumihonakatsu importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT hirotakaimai importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT yukikomuramoto importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT keikoshindo importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT hiroshisagara importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging AT yoshihirokawaoka importanceofthe17configurationofribonucleoproteincomplexesforinfluenzaavirusgenomepackaging
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Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging

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