WASP family proteins regulate the mobility of the B cell receptor during signaling activation

B cell receptors (BCR) capture antigen and initiate downstream antibody responses, but whether and how BCR signaling is regulated by BCR mobility is still unclear. Here the authors show, using single molecule imaging and machine learning analyses, that BCR and CD19 mobility is modulated by the actin...

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Autores principales: Ivan Rey-Suarez, Brittany A. Wheatley, Peter Koo, Anshuman Bhanja, Zhou Shu, Simon Mochrie, Wenxia Song, Hari Shroff, Arpita Upadhyaya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2a250cd833d54780bbb3012f5d131e7e
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