Stabilisation of half MCM ring by Cdt1 during DNA insertion

During pre-Replication Complex, eukaryotic cells load two MCMs into a head-to-head Double Hexamer around duplex DNA (DH). Here the authors preRC assembly assay with purified proteins to reveal insights into S. cerevisiae’s first steps that lead to the DH formation.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Marina Guerrero-Puigdevall, Narcis Fernandez-Fuentes, Jordi Frigola
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/2a3a272cd120490cb93389b9e9ed49dd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!