Stabilisation of half MCM ring by Cdt1 during DNA insertion

During pre-Replication Complex, eukaryotic cells load two MCMs into a head-to-head Double Hexamer around duplex DNA (DH). Here the authors preRC assembly assay with purified proteins to reveal insights into S. cerevisiae’s first steps that lead to the DH formation.

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Autores principales:	Marina Guerrero-Puigdevall, Narcis Fernandez-Fuentes, Jordi Frigola
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2a3a272cd120490cb93389b9e9ed49dd
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spelling	oai:doaj.org-article:2a3a272cd120490cb93389b9e9ed49dd2021-12-02T13:17:59ZStabilisation of half MCM ring by Cdt1 during DNA insertion10.1038/s41467-021-21932-82041-1723https://doaj.org/article/2a3a272cd120490cb93389b9e9ed49dd2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21932-8https://doaj.org/toc/2041-1723During pre-Replication Complex, eukaryotic cells load two MCMs into a head-to-head Double Hexamer around duplex DNA (DH). Here the authors preRC assembly assay with purified proteins to reveal insights into S. cerevisiae’s first steps that lead to the DH formation.Marina Guerrero-PuigdevallNarcis Fernandez-FuentesJordi FrigolaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marina Guerrero-Puigdevall Narcis Fernandez-Fuentes Jordi Frigola Stabilisation of half MCM ring by Cdt1 during DNA insertion
description	During pre-Replication Complex, eukaryotic cells load two MCMs into a head-to-head Double Hexamer around duplex DNA (DH). Here the authors preRC assembly assay with purified proteins to reveal insights into S. cerevisiae’s first steps that lead to the DH formation.
format	article
author	Marina Guerrero-Puigdevall Narcis Fernandez-Fuentes Jordi Frigola
author_facet	Marina Guerrero-Puigdevall Narcis Fernandez-Fuentes Jordi Frigola
author_sort	Marina Guerrero-Puigdevall
title	Stabilisation of half MCM ring by Cdt1 during DNA insertion
title_short	Stabilisation of half MCM ring by Cdt1 during DNA insertion
title_full	Stabilisation of half MCM ring by Cdt1 during DNA insertion
title_fullStr	Stabilisation of half MCM ring by Cdt1 during DNA insertion
title_full_unstemmed	Stabilisation of half MCM ring by Cdt1 during DNA insertion
title_sort	stabilisation of half mcm ring by cdt1 during dna insertion
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2a3a272cd120490cb93389b9e9ed49dd
work_keys_str_mv	AT marinaguerreropuigdevall stabilisationofhalfmcmringbycdt1duringdnainsertion AT narcisfernandezfuentes stabilisationofhalfmcmringbycdt1duringdnainsertion AT jordifrigola stabilisationofhalfmcmringbycdt1duringdnainsertion
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Stabilisation of half MCM ring by Cdt1 during DNA insertion

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