Stabilisation of half MCM ring by Cdt1 during DNA insertion
During pre-Replication Complex, eukaryotic cells load two MCMs into a head-to-head Double Hexamer around duplex DNA (DH). Here the authors preRC assembly assay with purified proteins to reveal insights into S. cerevisiae’s first steps that lead to the DH formation.
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Autores principales: | Marina Guerrero-Puigdevall, Narcis Fernandez-Fuentes, Jordi Frigola |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/2a3a272cd120490cb93389b9e9ed49dd |
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